Basic & Clinical Pharmacology /

Includes bibliographical references.

Section I: Basic Principles. Introduction: The Nature of Drugs & Drug Development & Regulation. Drug Receptors & Pharmacodynamics. Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action. Drug Biotransformation. Pharmacogenomics -- Section II: Autonomic Drugs. Introduction to Autonomic Pharmacology. Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs. Cholinoceptor-Blocking Drugs. Adrenoceptor Agonists & Sympathomimetic Drugs. Adrenoceptor Antagonist Drugs -- Section III: Cardiovascular-Renal Drugs. Antihypertensive Agents. Vasodilators & the Treatment of Angina Pectoris. Drugs Used in Heart Failure. Agents Used in Cardiac Arrhythmias. Diuretic Agents -- Section IV: Drugs With Important Actions On Smooth Muscle. Histamine, Serotonin, & the Ergot Alkaloids. Vasoactive Peptides. The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds. Nitric Oxide. Drugs Used in Asthma & Chronic Obstructive Pulmonary Disease -- Section V: Drugs That Act In The Central Nervous System. Introduction to the Pharmacology of CNS Drugs. Sedative-Hypnotic Drugs. The Alcohols. Antiseizure Drugs. General Anesthetics. Local Anesthetics. Skeletal Muscle Relaxants. Pharmacologic Management of Parkinsonism & Other Movement Disorders. Antipsychotic Agents & Lithium. Antidepressant Agents. Opioid Agonists & Antagonists. Drugs of Abuse -- Section VI: Drugs Used To Treat Diseases Of The Blood, Inflammation, & Gout. Agents Used in Cytopenias; Hematopoietic Growth Factors. Drugs Used in Disorders of Coagulation. Agents Used in Dyslipidemia. Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout --Section VII: Endocrine Drugs. Hypothalamic & Pituitary Hormones. Thyroid & Antithyroid Drugs. Adrenocorticosteroids & Adrenocortical Antagonists. The Gonadal Hormones & Inhibitors. Pancreatic Hormones & Glucose-Lowering Drugs. Agents That Affect Bone Mineral Homeostasis -- Section VIII: Chemotherapeutic Drugs. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, Oxazolidinones, & Pleuromutilins. Aminoglycosides & Spectinomycin. Sulfonamides, Trimethoprim, & Quinolones. Antimycobacterial Drugs. Antifungal Agents. Antiviral Agents. Miscellaneous Antimicrobial Agents; Disinfectants, Antiseptics, & Sterilants. Clinical Use of Antimicrobial Agents. Antiprotozoal Drugs. Pharmacology of the Antihelminthic Drugs. Cancer Chemotherapy. Immunopharmacology -- Section IX: Toxicology. Introduction to Toxicology: Occupational & Environmental. Heavy Metal Intoxication & Chelators. Management of the Poisoned Patient -- Section X: Special Topics. Special Aspects of Perinatal & Pediatric Pharmacology. Special Aspects of Geriatric Pharmacology. Dermatologic Pharmacology. Drugs Used in the Treatment of Gastrointestinal Diseases. Cannabinoid Drugs. Therapeutic & Toxic Potential of Over-the-Counter Agents. Dietary Supplements & Herbal Medications. Rational Prescribing & Prescription Writing. Important Drug Interactions & Their Mechanisms. Appendix: Vaccines, Immune Globulins, & Other Complex Biologic Products.

"The fifteenth edition continues the extensive use of full-color illustrations and expanded coverage of transporters, pharmacogenomics, and new drugs of all types. Case studies accompany most chapters. Basic & Clinical Pharmacology is designed to provide a comprehensive, authoritative, and readable pharmacology textbook for students in any of the health sciences." Preface.

Online resource (AccessMedicine, viewed October 27, 2020).