Fitzpatrick's dermatology in general medicine [electronic resource] / [edited by], Lowell A. Goldsmith, Stephen I. Katz, Barbara A. Gilchrest, Amy S. Paller, David J. Leffell, Klaus Wolff.

Includes bibliographical references and indexes.

Chapter 120. Merkel Cell Carcinoma -- Chapter 121. Mammary and Extramammary Paget"s Disease -- Section 22. Melanocytic Tumors -- Chapter 122. Benign Neoplasias and Hyperplasias of Melanocytes -- Chapter 123. Atypical (Dysplastic) Melanocytic Nevi -- Chapter 124. Cutaneous Melanoma -- Section 23. Tumors and Hyperplasias of the Dermis and Subcutaneous Fat -- Chapter 125. Malignant Fibrous, Fibrohistiocytic, and Histiocytic Tumors of the Dermis -- Chapter 126. Vascular Tumors -- Chapter 127. Neoplasias and Hyperplasias of Muscular and Neural Origin -- Chapter 128. Kaposi"s Sarcoma and Angiosarcoma -- Chapter 129. Neoplasms of Subcutaneous Fat -- Part 8. The Skin in Systemic Disease -- Section 24. Skin in Nutritional, Metabolic, and Heritable Disease -- Chapter 130. Cutaneous Changes in Nutritional Disease -- Chapter 131. Cutaneous Changes in Errors of Amino Acid Metabolism -- Chapter 132. The Porphyrias -- Chapter 133. Amyloidosis of the Skin -- Chapter 134. Systemic Autoinflammatory Diseases -- Chapter 135. Xanthomatoses and Lipoprotein Disorders -- Chapter 136. Fabry Disease -- Chapter 137. Lipoid Proteinosis and Heritable Disorders of Connective Tissue -- Chapter 138. Cutaneous Mineralization and Ossification -- Chapter 139. Hereditary Disorders of Genome Instability and DNA Repair -- Chapter 140. Tuberous Sclerosis Complex -- Chapter 141. The Neurofibromatoses -- Chapter 142. Ectodermal Dysplasias -- Chapter 143. Genetic Immunodeficiency Diseases -- Section 25. Skin Manifestations of Bone Marrow or Blood Chemistry Disorders -- Chapter 144. Hematologic Diseases -- Chapter 145. Cutaneous Lymphoma -- Chapter 146. Inflammatory Diseases that Simulate Lymphomas: Cutaneous Pseudolymphomas -- Chapter 147. Cutaneous Langerhans Cell Histiocytosis -- Chapter 148. Non-Langerhans Cell Histiocytosis -- Chapter 149. Mastocytosis -- Section 26. Skin Manifestations of Internal Organ Disorders -- Chapter 150. The Skin and Disorders of the Alimentary Tract, the Hepatobiliary System, the Kidney, and the Cardiopulmonary System -- Chapter 151. Diabetes Mellitus and Other Endocrine Diseases -- Chapter 152. Sarcoidosis -- Chapter 153. Cutaneous Manifestations of Internal Malignant Disease: Cutaneous Paraneoplastic Syndromes -- Section 27. The Skin in Vascular and Connective Tissue and Other Autoimmune Disorders -- Chapter 154. Mechanisms of Autoimmune Disease -- Chapter 155. Lupus Erythematosus -- Chapter 156. Dermatomyositis -- Chapter 157. Scleroderma -- Chapter 158. Scleredema and Scleromyxedema -- Chapter 159. Relapsing Polychondritis -- Chapter 160. Rheumatoid Arthritis, Rheumatic Fever, and Gout -- Chapter 161. Sjögren"s Syndrome -- Section 28. The Skin in Inflammatory and Other Vascular Disorders -- Chapter 162. Endothelium in Inflammation and Angiogenesis -- Chapter 163. Cutaneous Necrotizing Venulitis -- Chapter 164. Systemic Necrotizing Arteritis -- Chapter 165. Erythema Elevatum Diutinum -- Chapter 166. Adamantiades–Behçet Disease -- Chapter 167. Kawasaki Disease -- Chapter 168. Pigmented Purpuric Dermatoses -- Chapter 169. Cryoglobulinemia and Cryofibrinogenemia -- Chapter 170. Raynaud Phenomenon -- Chapter 171. Malignant Atrophic Papulosis (Degos Disease) -- Chapter 172. Vascular Malformations -- Chapter 173. Cutaneous Changes in Peripheral Arterial Vascular Disease -- Chapter 174. Cutaneous Changes in Peripheral Venous and Lymphatic Insufficiency -- Part 9. Disease Due to Microbial Agents, Infestations, Bites, and Stings -- Section 29. Bacterial Disease -- Chapter 175. General Considerations of Bacterial Diseases.

Chapter 176. Superficial Cutaneous Infections and Pyodermas -- Chapter 177. Gram-Positive Infections Associated with Toxin Production -- Chapter 178. Non-Necrotizing Infections of the Dermis and Subcutaneous Fat: Cellulitis and Erysipelas -- Chapter 179. Necrotizing Soft Tissue Infections: Necrotizing Fasciitis, Gangrenous Cellulitis, and Myonecrosis -- Chapter 180. Gram-Negative Coccal and Bacillary Infections -- Chapter 181. The Skin in Infective Endocarditis, Sepsis, Septic Shock, and Disseminated Intravascular Coagulation -- Chapter 182. Bartonellosis -- Chapter 183. Miscellaneous Bacterial Infections with Cutaneous Manifestations -- Chapter 184. Tuberculosis and Infections with Atypical Mycobacteria -- Chapter 185. Actinomycosis, Nocardiosis, and Actinomycetoma -- Chapter 186. Leprosy -- Chapter 187. Lyme Borreliosis -- Section 30. Fungal Diseases -- Chapter 188. Superficial Fungal Infection -- Chapter 189. Yeast Infections: Candidiasis, Tinea (Pityriasis) Versicolor, and Malassezia ( Pityrosporum ) Folliculitis -- Chapter 190. Deep Fungal Infections -- Section 31. Viral and Rickettsial Diseases -- Chapter 191. General Considerations of Viral Diseases -- Chapter 192. Exanthematous Viral Diseases -- Chapter 193. Herpes Simplex -- Chapter 194. Varicella and Herpes Zoster -- Chapter 195. Poxvirus Infections -- Chapter 196. Human Papilloma Virus Infections -- Chapter 197. Human T-Lymphotropic Viruses -- Chapter 198. Cutaneous Manifestations of Human Immunodeficiency Virus Disease -- Chapter 199. The Rickettsioses, Ehrlichioses, and Anaplasmoses -- Section 32. Sexually Transmitted Diseases -- Chapter 200. Syphilis -- Chapter 201. Endemic (Nonvenereal) Treponematoses -- Chapter 202. Chancroid -- Chapter 203. Lymphogranuloma Venereum -- Chapter 204. Granuloma Inguinale -- Chapter 205. Gonorrhea, Mycoplasma, and Vaginosis -- Section 33. Infestations, Bites, and Stings -- Chapter 206. Leishmaniasis and Other Protozoan Infections -- Chapter 207. Helminthic Infections -- Chapter 208. Scabies, Other Mites, and Pediculosis -- Chapter 209. Bites and Stings of Terrestrial and Aquatic Life -- Chapter 210. Arthropod Bites and Stings -- Part 10. Occupational Skin Diseases and Skin Diseases Due to Biologic Warfare -- Section 34. Occupational Skin Diseases -- Chapter 211. Occupational Skin Diseases Due to Irritants and Allergens -- Chapter 212. Occupational Noneczematous Skin Diseases Due to Biologic, Physical, and Chemical Agents: Introduction -- Section 35. The Skin in Bioterrorism and Biologic Warfare -- Chapter 213. Cutaneous Manifestations of Biologic, Chemical, and Radiologic Attacks -- Part 11. Therapeutics -- Section 36. Topical Therapy -- Chapter 214. Principles of Topical Therapy -- Chapter 215. Pharmacokinetics and Topical Applications of Drugs -- Chapter 216. Topical Corticosteroids -- Chapter 217. Topical Retinoids -- Chapter 218. Topical Antibiotics -- Chapter 219. Topical Antifungal Agents -- Chapter 220. Topical and Intralesional Cytotoxic Agents -- Chapter 221. Topical Immunomodulators -- Chapter 222. Other Topical Medications -- Chapter 223. Photoprotection -- Section 37. Systemic Therapy -- Chapter 224. Systemic Glucocorticoids -- Chapter 225. Dapsone -- Chapter 226. Aminoquinolines -- Chapter 227. Cytotoxic and Antimetabolic Agents -- Chapter 228. Retinoids -- Chapter 229. Antihistamines -- Chapter 230. Antibiotics -- Chapter 231. Antiviral Drugs -- Chapter 232. Oral Antifungal Agents.

Chapter 233. Immunosuppressive and Immunomodulatory Drugs -- Chapter 234. Immunobiologicals, Cytokines, and Growth Factors in Dermatology -- Chapter 235. Antiangiogenic Agents -- Chapter 236. Drug Interactions -- Section 38. Physical Treatments -- Chapter 237. Phototherapy -- Chapter 238. Photochemotherapy and Photodynamic Therapy -- Chapter 239. Lasers and Flashlamps in Dermatology -- Chapter 240. Radiotherapy -- Section 39. Complementary and Alternative Dermatology -- Chapter 241. Complementary and Alternative Medicine in Dermatology -- Section 40. Surgery in Dermatology -- Chapter 242. Anatomy and Approach in Dermatologic Surgery -- Chapter 243. Excisional Surgery and Repair, Flaps, and Grafts -- Chapter 244. Mohs Micrographic Surgery -- Chapter 245. Nail Surgery -- Chapter 246. Cryosurgery and Electrosurgery -- Chapter 247. Surgical Complications -- Chapter 248. Mechanisms of Wound Repair, Wound Healing, and Wound Dressing -- Chapter 249. Treatment for Varicose and Telangiectatic Leg Veins -- Section 41. Cosmetic Dermatology -- Chapter 250. Cosmetics and Skin Care in Dermatology -- Chapter 251. Ablative Lasers, Chemical Peels, and Dermabrasion -- Chapter 252. Cosmetic Applications of Nonablative Lasers and Other Light Devices -- Chapter 253. Liposuction -- Chapter 254. Soft Tissue Augmentation -- Chapter 255. Botulinum Toxin -- Chapter 256. Hair Transplantation and Alopecia Reduction.

Chapter 64. Morphea -- Chapter 65. Lichen Sclerosus -- Chapter 66. Dermal Hypertrophies and Benign Fibroblastic/Myofibroblastic Tumors -- Chapter 67. Anetoderma and Other Atrophic Disorders of the Skin -- Chapter 68. Ainhum and Pseudoainhum -- Chapter 69. Acquired Perforating Disorders -- Section 10. Disorders of Subcutaneous Tissue -- Chapter 70. Panniculitis -- Chapter 71. Lipodystrophy -- Section 11. Disorders of Melanocytes -- Chapter 72. Biology of Melanocytes -- Chapter 73. Albinism and Other Genetic Disorders of Pigmentation -- Chapter 74. Vitiligo -- Chapter 75. Hypomelanoses and Hypermelanoses -- Section 12. Disorders of the Oral and Genital Integument -- Chapter 76. Biology and Pathology of the Oral Cavity -- Chapter 77. Diseases and Disorders of the Male Genitalia -- Chapter 78. Diseases and Disorders of the Female Genitalia -- Part 3. Disorders of the Skin Appendages -- Section 13. Disorders of the Sebaceous Glands -- Chapter 79. Biology of Sebaceous Glands -- Chapter 80. Acne Vulgaris and Acneiform Eruptions -- Chapter 81. Rosacea -- Chapter 82. Perioral Dermatitis -- Section 14. Disorders of the Eccrine and Apocrine Glands -- Chapter 83. Biology of Eccrine and Apocrine Glands -- Chapter 84. Disorders of the Eccrine Sweat Glands and Sweating -- Chapter 85. Disorders of the Apocrine Sweat Glands -- Section 15. Disorders of the Hair and Nails -- Chapter 86. Biology of Hair Follicles -- Chapter 87. Keratosis Pilaris and Other Inflammatory Follicular Keratotic Syndromes -- Chapter 88. Hair Growth Disorders -- Chapter 89. Biology of Nails and Nail Disorders -- Part 4. Disorders Due to the Environment -- Section 16. Disorders Due to Ultraviolet Radiation -- Chapter 90. Fundamentals of Cutaneous Photobiology and Photoimmunology -- Chapter 91. Abnormal Responses to Ultraviolet Radiation: Idiopathic, Probably Immunologic, and Photoexacerbated -- Chapter 92. Abnormal Responses to Ultraviolet Radiation: Photosensitivity Induced by Exogenous Agents -- Section 17. Skin Changes Due to Other Physical and Chemical Factors -- Chapter 93. Thermoregulation -- Chapter 94. Cold Injuries -- Chapter 95. Thermal Injuries -- Chapter 96. Skin Problems in Amputees -- Chapter 97. Skin Problems in Ostomates -- Chapter 98. Corns and Calluses -- Chapter 99. Sports Dermatology -- Chapter 100. Decubitus (Pressure) Ulcers -- Chapter 101. Body ART -- Part 5. Neurocutaneous and Psychocutaneous Aspects of Skin Disease -- Section 18. Neurocutaneous and Psychocutaneous Skin Disease -- Chapter 102. Neurobiology of the Skin -- Chapter 103. Pathophysiology and Clinical Aspects of Pruritus -- Chapter 104. Psychocutaneous Skin Disease -- Chapter 105. Cutaneous Manifestations of Drug Abuse -- Chapter 106. Skin Signs of Physical Abuse -- Part 6. Skin Changes across the Span of Life -- Section 19. From Birth to Old Age -- Chapter 107. Neonatal, Pediatric, and Adolescent Dermatology -- Chapter 108. Skin Changes and Diseases in Pregnancy -- Chapter 109. Aging of Skin -- Part 7. Neoplasia -- Section 20. Carcinogenesis -- Chapter 110. Genome Instability, DNA Repair, and Cancer -- Chapter 111. Chemical Carcinogenesis -- Chapter 112. Ultraviolet Radiation Carcinogenesis -- Section 21. Epidermal and Appendageal Tumors -- Chapter 113. Epithelial Precancerous Lesions -- Chapter 114. Squamous Cell Carcinoma -- Chapter 115. Basal Cell Carcinoma -- Chapter 116. Basal Cell Nevus Syndrome -- Chapter 117. Keratoacanthoma -- Chapter 118. Benign Epithelial Tumors, Hamartomas, and Hyperplasias -- Chapter 119. Appendage Tumors and Hamartomas of the Skin.

Part 1. Introduction -- Section 1. General Considerations -- Chapter 1. The Epidemiology and Burden of Skin Disease -- Chapter 2. Evidence-Based Dermatology -- Chapter 3. Global Health in Dermatology -- Chapter 4. Public Health in Dermatology -- Section 2. Approach to Dermatologic Diagnosis -- Chapter 5. Structure of Skin Lesions and Fundamentals of Clinical Diagnosis -- Chapter 6. Basic Pathologic Reactions of the Skin -- Section 3. Overview of Biology, Development, and Structure of Skin -- Chapter 7. Development and Structure of Skin -- Chapter 8. Genetics in Relation to the Skin -- Chapter 9. Racial Considerations: Skin of Color -- Part 2. Disorders Presenting in Skin and Mucous Membranes -- Section 4. Inflammatory Disorders Based on T -- Cell Reactivity and Dysregulation -- Chapter 10. Innate and Adaptive Immunity in the Skin -- Chapter 11. Cytokines -- Chapter 12. Chemokines -- Chapter 13. Allergic Contact Dermatitis -- Chapter 14. Atopic Dermatitis (Atopic Eczema) -- Chapter 15. Nummular Eczema, Lichen Simplex Chronicus, and Prurigo Nodularis -- Chapter 16. Vesicular Palmoplantar Eczema -- Chapter 17. Autosensitization Dermatitis -- Chapter 18. Psoriasis -- Chapter 19. Psoriatic Arthritis -- Chapter 20. Reactive Arthritis -- Chapter 21. Pustular Eruptions of Palms and Soles -- Chapter 22. Seborrheic Dermatitis -- Chapter 23. Exfoliative Dermatitis -- Chapter 24. Pityriasis Rubra Pilaris -- Chapter 25. Parapsoriasis and Pityriasis Lichenoides -- Chapter 26. Lichen Planus -- Chapter 27. Lichen Nitidus -- Chapter 28. Graft-versus-Host Disease -- Chapter 29. Skin Disease in Acute and Chronic Immunosuppression -- Section 5. Inflammatory Diseases Based on Neutrophils and Eosinophils -- Chapter 30. Regulation of the Production and Activation of Neutrophils -- Chapter 31. Regulation of the Production and Activation of Eosinophils -- Chapter 32. Acute Febrile Neutrophilic Dermatosis (Sweet Syndrome) -- Chapter 33. Pyoderma Gangrenosum -- Chapter 34. Granuloma Faciale -- Chapter 35. Subcorneal Pustular Dermatosis (Sneddon–Wilkinson Disease) -- Chapter 36. Eosinophils in Cutaneous Diseases -- Section 6. Inflammatory Diseases Based on Abnormal Humoral Reactivity and Other Inflammatory Diseases -- Chapter 37. Humoral Immunity and Complement -- Chapter 38. Urticaria and Angioedema -- Chapter 39. Erythema Multiforme -- Chapter 40. Epidermal Necrolysis (Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis) -- Chapter 41. Cutaneous Reactions to Drugs -- Chapter 42. Pityriasis Rosea -- Chapter 43. Erythema Annulare Centrifugum and Other Figurate Erythemas -- Chapter 44. Granuloma Annulare -- Section 7. Disorders of Epidermal Differentiation and Keratinization -- Chapter 45. Epidermal Stem Cells -- Chapter 46. Epidermal Growth and Differentiation -- Chapter 47. Skin as an Organ of Protection -- Chapter 48. Irritant Contact Dermatitis -- Chapter 49. The Ichthyoses -- Chapter 50. Inherited Palmoplantar Keratodermas -- Chapter 51. Acantholytic Disorders of the Skin -- Chapter 52. Porokeratosis -- Section 8. Disorders of Epidermal and Dermal-Epidermal Adhesion and Vesicular and Bullous Disorders -- Chapter 53. Epidermal and Epidermal–Dermal Adhesion -- Chapter 54. Pemphigus -- Chapter 55. Paraneoplastic Pemphigus -- Chapter 56. Bullous Pemphigoid -- Chapter 57. Cicatricial Pemphigoid -- Chapter 58. Linear Immunoglobulin A Dermatosis and Chronic Bullous Disease of Childhood -- Chapter 59. Pemphigoid Gestationis (Herpes Gestationis) -- Chapter 60. Epidermolysis Bullosa Acquisita -- Chapter 61. Dermatitis Herpetiformis -- Chapter 62. Inherited Epidermolysis Bullosa -- Section 9. Disorders of the Dermal Connective Tissue -- Chapter 63. Collagens, Elastic Fibers, and Other Extracellular Matrix Proteins of the Dermis.

"Generations of clinicians, skin biologists, residents, and educators have acclaimed Fitzpatrick's as the most authoritative and complete guide to dermatologic basic sciences, histopathology, diagnosis, and treatment. Edition after edition, it reflects the latest insights into skin diseases and skin biology--and their practical relevance to general internal medicine--while covering the scientific foundations of the specialty. This classic yet cutting-edge text is supported by the expert insights of more than 500 internationally respected contributors, and it covers everything dermatologists need to know about skin, dermatologic signs of underlying disease, and the management of all skin diseases, including acne, skin cancer, and psoriasis. Features: More than 3000 full-color photographs ; DVD with image bank includes downloadable figures from the text ; New illustration style makes difficult concepts easier to understand ; Therapeutic ladders with first, second, and third line therapies ; New or thoroughly revised chapters on Psoriasis; Skin disease in immunosuppressed patients; Epidermal stem cells; Hair growth disorders; Neonatal, pediatric, and adolescent dermatology; Radiotherapy; Immunobiologicals and cytokines; Lasers for rejuvenation ; Expanded medical and surgical therapeutics sections guide you through all treatment options." -- Publisher's website.

Also issued in Online and PDF version.

Description based on cover image and table of contents, viewed on Oct. 20, 2016.