Harrison's principles of internal medicine [electronic resource] / Dan L. Longo, Editor ... [et al.].

Includes appendix.

Includes bibliographical references and indexes.

Part 1: General Considerations in Clinical Medicine -- 1: The Practice of Medicine -- 2: Global Issues in Medicine -- 3: Decision-Making in Clinical Medicine -- 4: Screening and Prevention of Disease -- 5: Principles of Clinical Pharmacology -- 6e: Women’s Health -- 7e: Men’s Health -- 8: Medical Disorders During Pregnancy -- 9: Medical Evaluation of the Surgical Patient -- 10: Palliative and End-of-Life Care -- 11: Clinical Problems of Aging -- 12e: The Safety and Quality of Health Care -- 13e: Primary Care in Low- and Middle-Income Countries -- 14e: Complementary, Alternative, and Integrative Health Practices -- 15e: The Economics of Medical Care -- 16e: Racial and Ethnic Disparities in Health Care -- 17e: Ethical Issues in Clinical Medicine -- Part 2: Cardinal Manifestations and Presentation of Diseases -- Section 1: Pain -- 18: Pain: Pathophysiology and Management -- 19: Chest Discomfort -- 20: Abdominal Pain -- 21: Headache -- 22: Back and Neck Pain -- Section 2: Alterations in Body Temperature -- 23: Fever -- 24: Fever and Rash -- 25e: Atlas of Rashes Associated with Fever -- 26: Fever of Unknown Origin -- Section 3: Nervous System Dysfunction -- 27: Syncope -- 28: Dizziness and Vertigo -- 29: Fatigue -- 30: Neurologic Causes of Weakness and Paralysis -- 31: Numbness, Tingling, and Sensory Loss -- 32: Gait and Balance Disorders -- 33e: Video Library of Gait Disorders -- 34: Confusion and Delirium -- 35: Dementia -- 36: Aphasia, Memory Loss, and Other Focal Cerebral Disorders -- 37e: Primary Progressive Aphasia, Memory Loss, and Other Focal Cerebral Disorders -- 38: Sleep Disorders -- Section 4: Disorders of Eyes, Ears, Nose, and Throat -- 39: Disorders of the Eye -- 40e: Use of the Hand-Held Ophthalmoscope -- 41e: Video Library of Neuro-Ophthalmology -- 42: Disorders of Smell and Taste -- 43: Disorders of Hearing -- 44: Sore Throat, Earache, and Upper Respiratory Symptoms -- 45: Oral Manifestations of Disease -- 46e: Atlas of Oral Manifestations of Disease -- Section 5: Alterations in Circulatory and Respiratory Functions -- 47e: Dyspnea -- 48: Cough and Hemoptysis -- 49: Hypoxia and Cyanosis -- 50: Edema -- 51e: Approach to the Patient with a Heart Murmur -- 52: Palpitations -- Section 6: Alterations in Gastrointestinal Function -- 53: Dysphagia -- 54: Nausea, Vomiting, and Indigestion -- 55: Diarrhea and Constipation -- 56: Involuntary Weight Loss -- 57: Gastrointestinal Bleeding -- 58: Jaundice -- 59: Abdominal Swelling and Ascites -- Section 7: Alterations in Renal and Urinary Tract Function -- 60e: Dysuria, Bladder Pain, and the Interstitial Cystitis/Bladder Pain Syndrome -- 61: Azotemia and Urinary Abnormalities -- 62e: Atlas of Urinary Sediments and Renal Biopsies -- 63: Fluid and Electrolyte Disturbances -- 64e: Fluid and Electrolyte Imbalances and Acid-Base Disturbances: Case Examples -- 65: Hypercalcemia and Hypocalcemia -- 66: Acidosis and Alkalosis -- Section 8: Alterations in Sexual Function and Reproduction -- 67: Sexual Dysfunction -- 68: Hirsutism -- 69: Menstrual Disorders and Pelvic Pain -- Section 9: Alterations in the Skin -- 70: Approach to the Patient with a Skin Disorder -- 71: Eczema, Psoriasis, Cutaneous Infections, Acne, and Other Common Skin Disorders -- 72: Skin Manifestations of Internal Disease -- 73: Immunologically Mediated Skin Diseases -- 74: Cutaneous Drug Reactions -- 75: Photosensitivity and Other Reactions to Light -- 76e: Atlas of Skin Manifestations of Internal Disease -- Section 10: Hematologic Alterations.

77: Anemia and Polycythemia -- 78: Bleeding and Thrombosis -- 79: Enlargement of Lymph Nodes and Spleen -- 80: Disorders of Granulocytes and Monocytes -- 81e: Atlas of Hematology and Analysis of Peripheral Blood Smears -- Part 3: Genes, the Environment, and Disease -- 82: Genes, the Environment, and Disease -- 83e: Chromosome Disorders -- 84: The Practice of Genetics in Clinical Medicine -- 85e: Mitochondrial DNA and Heritable Traits and Diseases -- 86e: The Human Microbiome -- 87e: Network Medicine: Systems Biology in Health and Disease -- Part 4: Regenerative Medicine -- 88: Stem Cell Biology -- 89e: Hematopoietic Stem Cells -- 90e: Applications of Stem Cell Biology in Clinical Medicine -- 91e: Gene Therapy in Clinical Medicine -- 92e: Tissue Engineering -- Part 5: Aging -- 93e: World Demography of Aging -- 94e: The Biology of Aging -- Part 6: Nutrition and Weight Loss -- 95e: Nutrient Requirements and Dietary Assessment -- 96e: Vitamin and Trace Mineral Deficiency and Excess -- 97: Malnutrition and Nutritional Assessment -- 98e: Enteral and Parenteral Nutrition Therapy -- Part 7: Oncology and Hematology -- Section 1: Neoplastic Disorders -- 99: Approach to the Patient with Cancer -- 100: Prevention and Early Detection of Cancer -- 101e: Cancer Genetics -- 102e: Cancer Cell Biology -- 103e: Principles of Cancer Treatment -- 104: Infections in Patients with Cancer -- 105: Cancer of the Skin -- 106: Head and Neck Cancer -- 107: Neoplasms of the Lung -- 108: Breast Cancer -- 109: Upper Gastrointestinal Tract Cancers -- 110: Lower Gastrointestinal Cancers -- 111: Tumors of the Liver and Biliary Tree -- 112: Pancreatic Cancer -- 113: Endocrine Tumors of the Gastrointestinal Tract and Pancreas -- 114: Bladder and Renal Cell Carcinomas -- 115: Benign and Malignant Diseases of the Prostate -- 116: Testicular Cancer -- 117: Gynecologic Malignancies -- 118: Primary and Metastatic Tumors of the Nervous System -- 119e: Soft Tissue and Bone Sarcomas and Bone Metastases -- 120e: Carcinoma of Unknown Primary -- 121: Paraneoplastic Syndromes: Endocrinologic/Hematologic -- 122: Paraneoplastic Neurologic Syndromes and Autoimmune Encephalitis -- 123e: Thymoma -- 124e: Neoplasia During Pregnancy -- 125: Late Consequences of Cancer and Its Treatment -- Section 2: Hematopoietic Disorders -- 126: Iron Deficiency and Other Hypoproliferative Anemias -- 127: Disorders of Hemoglobin -- 128: Megaloblastic Anemias -- 129: Hemolytic Anemias and Anemia Due to Acute Blood Loss -- 130: Bone Marrow Failure Syndromes Including Aplastic Anemia and Myelodysplasia -- 131: Polycythemia Vera and Other Myeloproliferative Neoplasms -- 132: Acute Myeloid Leukemia -- 133: Chronic Myeloid Leukemia -- 134: Malignancies of Lymphoid Cells -- 135e: Less Common Hematologic Malignancies -- 136: Plasma Cell Disorders -- 137: Amyloidosis -- 138e: Transfusion Biology and Therapy -- 139e: Hematopoietic Cell Transplantation -- 140: Disorders of Platelets and Vessel Wall -- 141: Coagulation Disorders -- 142: Arterial and Venous Thrombosis -- 143: Antiplatelet, Anticoagulant, and Fibrinolytic Drugs -- Part 8: Infectious Diseases -- Section 1: Basic Considerations in Infectious Diseases -- 144: Approach to the Patient with an Infectious Disease -- 145e: Molecular Mechanisms of Microbial Pathogenesis -- 146: Genomics and Infectious Disease -- 147: Approach to the Acutely Ill Infected Febrile Patient -- 148: Immunization Principles and Vaccine Use -- 149: Health Recommendations for International Travel -- 150e: Laboratory Diagnosis of Infectious Diseases -- 151e: Climate Change and Infectious Disease -- 152e: Infections in Veterans Returning from Foreign Wars.

Section 2: Clinical Syndromes: Community-Acquired Infections -- 153: Pneumonia -- 154: Lung Abscess -- 155: Infective Endocarditis -- 156: Infections of the Skin, Muscles, and Soft Tissues -- 157: Infectious Arthritis -- 158: Osteomyelitis -- 159: Intraabdominal Infections and Abscesses -- 160: Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning -- 161: Clostridium difficile Infection, Including Pseudomembranous Colitis -- 162: Urinary Tract Infections, Pyelonephritis, and Prostatitis -- 163: Sexually Transmitted Infections: Overview and Clinical Approach -- 164: Meningitis, Encephalitis, Brain Abscess, and Empyema -- 165: Chronic and Recurrent Meningitis -- 166e: Infectious Complications of Burns -- 167e: Infectious Complications of Bites -- Section 3: Clinical Syndromes: Health Care-Associated Infections -- 168: Infections Acquired in Health Care Facilities -- 169: Infections in Transplant Recipients -- Section 4: Approach to Therapy for Bacterial Diseases -- 170: Treatment and Prophylaxis of Bacterial Infections -- Section 5: Diseases Caused by Gram-Positive Bacteria -- 171: Pneumococcal Infections -- 172: Staphylococcal Infections -- 173: Streptococcal Infections -- 174: Enterococcal Infections -- 175: Diphtheria and Other Corynebacterial Infections -- 176: Listeria monocytogenes Infections -- 177: Tetanus -- 178: Botulism -- 179: Gas Gangrene and Other Clostridial Infections -- Section 6: Diseases Caused by Gram-Negative Bacteria -- 180: Meningococcal Infections -- 181: Gonococcal Infections -- 182: Haemophilus and Moraxella Infections -- 183e: Infections Due to the HACEK Group and Miscellaneous Gram-Negative Bacteria -- 184: Legionella Infections -- 185: Pertussis and Other Bordetella Infections -- 186: Diseases Caused by Gram-Negative Enteric Bacilli -- 187: Acinetobacter Infections -- 188: Helicobacter pylori Infections -- 189: Infections Due to Pseudomonas Species and Related Organisms -- 190: Salmonellosis -- 191: Shigellosis -- 192: Infections Due to Campylobacter and Related Organisms -- 193: Cholera and Other Vibrioses -- 194e: Brucellosis -- 195: Tularemia -- 196: Plague and Other Yersinia Infections -- 197: Bartonella Infections, Including Cat-Scratch Disease -- 198e: Donovanosis -- Section 7: Miscellaneous Bacterial Infections -- 199: Nocardiosis -- 200: Actinomycosis and Whipple’s Disease -- 201: Infections Due to Mixed Anaerobic Organisms -- Section 8: Mycobacterial Diseases -- 202: Tuberculosis -- 203: Leprosy -- 204: Nontuberculous Mycobacterial Infections -- 205e: Antimycobacterial Agents -- Section 9: Spirochetal Diseases -- 206: Syphilis -- 207e: Endemic Treponematoses -- 208: Leptospirosis -- 209: Relapsing Fever -- 210: Lyme Borreliosis -- Section 10: Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae -- 211: Rickettsial Diseases -- 212: Infections Due to Mycoplasmas -- 213: Chlamydial Infections -- Section 11: Viral Diseases: General Considerations -- 214e: Medical Virology -- 215e: Antiviral Chemotherapy, Excluding Antiretroviral Drugs -- Section 12: Infections Due to DNA Viruses -- 216: Herpes Simplex Virus Infections -- 217: Varicella-Zoster Virus Infections -- 218: Epstein-Barr Virus Infections, Including Infectious Mononucleosis -- 219: Cytomegalovirus and Human Herpesvirus Types 6, 7, and 8 -- 220e: Molluscum Contagiosum, Monkeypox, and Other Poxvirus Infections -- 221: Parvovirus Infections -- 222: Human Papillomavirus Infections -- Section 13: Infections Due to DNA and RNA Respiratory Viruses -- 223: Common Viral Respiratory Infections -- 224: Influenza -- Section 14: Infections Due to Human Immunodeficiency Virus and Other Human Retroviruses.

225e: The Human Retroviruses -- 226: Human Immunodeficiency Virus Disease: AIDS and Related Disorders -- Section 15: Infections Due to RNA Viruses -- 227: Viral Gastroenteritis -- 228: Enterovirus, Parechovirus, and Reovirus Infections -- 229: Measles (Rubeola) -- 230e: Rubella (German Measles) -- 231e: Mumps -- 232: Rabies and Other Rhabdovirus Infections -- 233: Arthropod-Borne and Rodent-Borne Virus Infections -- 234: Ebolavirus and Marburgvirus Infections -- Section 16: Fungal Infections -- 235: Diagnosis and Treatment of Fungal Infections -- 236: Histoplasmosis -- 237: Coccidioidomycosis -- 238: Blastomycosis -- 239: Cryptococcosis -- 240: Candidiasis -- 241: Aspergillosis -- 242: Mucormycosis -- 243: Superficial Mycoses and Less Common Systemic Mycoses -- 244: Pneumocystis Infections -- Section 17: Protozoal and Helminthic Infections: General Considerations -- 245e: Laboratory Diagnosis of Parasitic Infections -- 246e: Agents Used to Treat Parasitic Infections -- Section 18: Protozoal Infections -- 247: Amebiasis and Infection with Free-Living Amebas -- 248: Malaria -- 249: Babesiosis -- 250e: Atlas of Blood Smears of Malaria and Babesiosis -- 251: Leishmaniasis -- 252: Chagas Disease and African Trypanosomiasis -- 253: Toxoplasma Infections -- 254: Protozoal Intestinal Infections and Trichomoniasis -- Section 19: Helminthic Infections -- 255e: Introduction to Helminthic Infections -- 256: Trichinellosis and Other Tissue Nematode Infections -- 257: Intestinal Nematode Infections -- 258: Filarial and Related Infections -- 259: Schistosomiasis and Other Trematode Infections -- 260: Cestode Infections -- Part 9: Terrorism and Clinical Medicine -- 261e: Microbial Bioterrorism -- 262e: Chemical Terrorism -- 263e: Radiation Terrorism -- Part 10: Disorders of the Cardiovascular System -- Section 1: Introduction to Cardiovascular Disorders -- 264: Approach to the Patient with Possible Cardiovascular Disease -- 265e: Basic Biology of the Cardiovascular System -- 266e: Epidemiology of Cardiovascular Disease -- Section 2: Diagnosis of Cardiovascular Disorders -- 267: Physical Examination of the Cardiovascular System -- 268: Electrocardiography -- 269e: Atlas of Electrocardiography -- 270e: Noninvasive Cardiac Imaging: Echocardiography, Nuclear Cardiology, and Magnetic Resonance/Computed Tomography Imaging -- 271e: Atlas of Noninvasive Imaging -- 272: Diagnostic Cardiac Catheterization and Coronary Angiography -- Section 3: Disorders of Rhythm -- 273e: Principles of Electrophysiology -- 274: The Bradyarrhythmias: Disorders of the Sinoatrial Node -- 275: The Bradyarrhythmias: Disorders of the Atrioventricular Node -- 276: Supraventricular Tachyarrhythmias -- 277: Ventricular Arrhythmias -- 278e: Atlas of Cardiac Arrhythmias -- Section 4: Disorders of the Heart -- 279: Heart Failure: Pathophysiology and Diagnosis -- 280: Heart Failure: Management -- 281: Cardiac Transplantation and Prolonged Assisted Circulation -- 282: Congenital Heart Disease in the Adult -- 283: Aortic Valve Disease -- 284: Mitral Valve Disease -- 285: Tricuspid and Pulmonic Valve Disease -- 286: Multiple and Mixed Valvular Heart Disease -- 287: Cardiomyopathy and Myocarditis -- 288: Pericardial Disease -- 289e: Tumors and Trauma of the Heart -- 290e: Cardiac Manifestations of Systemic Disease -- Section 5: Coronary and Peripheral Vascular Disease -- 291e: The Pathogenesis, Prevention, and Treatment of Atherosclerosis -- 292e: Atlas of Atherosclerosis -- 293: Ischemic Heart Disease -- 294: Non-ST-Segment Elevation Acute Coronary Syndrome (Non-ST-Segment Elevation Myocardial Infarction and Unstable Angina) -- 295: ST-Segment Elevation Myocardial Infarction -- 296e: Percutaneous Coronary Interventions and Other Interventional Procedures -- 297e: Atlas of Percutaneous Revascularization -- 298: Hypertensive Vascular Disease -- 299: Renovascular Disease -- 300: Deep Venous Thrombosis and Pulmonary Thromboembolism.

301: Diseases of the Aorta -- 302: Arterial Diseases of the Extremities -- 303: Chronic Venous Disease and Lymphedema -- 304: Pulmonary Hypertension -- Part 11: Disorders of the Respiratory System -- Section 1: Diagnosis of Respiratory Disorders -- 305: Approach to the Patient with Disease of the Respiratory System -- 306e: Disturbances of Respiratory Function -- 307: Diagnostic Procedures in Respiratory Disease -- 308e: Atlas of Chest Imaging -- Section 2: Diseases of the Respiratory System -- 309: Asthma -- 310: Hypersensitivity Pneumonitis and Pulmonary Infiltrates with Eosinophilia -- 311: Occupational and Environmental Lung Disease -- 312: Bronchiectasis -- 313: Cystic Fibrosis -- 314: Chronic Obstructive Pulmonary Disease -- 315: Interstitial Lung Diseases -- 316: Disorders of the Pleura -- 317: Disorders of the Mediastinum -- 318: Disorders of Ventilation -- 319: Sleep Apnea -- 320e: Lung Transplantation -- Part 12: Critical Care Medicine -- Section 1: Respiratory Critical Care -- 321: Approach to the Patient with Critical Illness -- 322: Acute Respiratory Distress Syndrome -- 323: Mechanical Ventilatory Support -- Section 2: Shock and Cardiac Arrest -- 324: Approach to the Patient with Shock -- 325: Severe Sepsis and Septic Shock -- 326: Cardiogenic Shock and Pulmonary Edema -- 327: Cardiovascular Collapse, Cardiac Arrest, and Sudden Cardiac Death -- Section 3: Neurologic Critical Care -- 328: Coma -- 329e: Examination of the Comatose Patient -- 330: Neurologic Critical Care, Including Hypoxic-Ischemic Encephalopathy, and Subarachnoid Hemorrhage -- Section 4: Oncologic Emergencies -- 331: Oncologic Emergencies -- Part 13: Disorders of the Kidney and Urinary Tract -- 332e: Cellular and Molecular Biology of the Kidney -- 333e: Adaptation of the Kidney to Injury -- 334: Acute Kidney Injury -- 335: Chronic Kidney Disease -- 336: Dialysis in the Treatment of Renal Failure -- 337: Transplantation in the Treatment of Renal Failure -- 338: Glomerular Diseases -- 339: Polycystic Kidney Disease and Other Inherited Disorders of Tubule Growth and Development -- 340: Tubulointerstitial Diseases of the Kidney -- 341: Vascular Injury to the Kidney -- 342: Nephrolithiasis -- 343: Urinary Tract Obstruction -- Part 14: Disorders of the Gastrointestinal System -- Section 1: Disorders of the Alimentary Tract -- 344: Approach to the Patient with Gastrointestinal Disease -- 345: Gastrointestinal Endoscopy -- 346e: Video Atlas of Gastrointestinal Endoscopy -- 347: Diseases of the Esophagus -- 348: Peptic Ulcer Disease and Related Disorders -- 349: Disorders of Absorption -- 350e: The Schilling Test -- 351: Inflammatory Bowel Disease -- 352: Irritable Bowel Syndrome -- 353: Diverticular Disease and Common Anorectal Disorders -- 354: Mesenteric Vascular Insufficiency -- 355: Acute Intestinal Obstruction -- 356: Acute Appendicitis and Peritonitis -- Section 2: Liver and Biliary Tract Disease -- 357: Approach to the Patient with Liver Disease -- 358: Evaluation of Liver Function -- 359: The Hyperbilirubinemias -- 360: Acute Viral Hepatitis -- 361: Toxic and Drug-Induced Hepatitis -- 362: Chronic Hepatitis -- 363: Alcoholic Liver Disease -- 364: Nonalcoholic Fatty Liver Diseases and Nonalcoholic Steatohepatitis -- 365: Cirrhosis and Its Complications -- 366e: Atlas of Liver Biopsies -- 367e: Genetic, Metabolic, and Infiltrative Diseases Affecting the Liver -- 368: Liver Transplantation -- 369: Diseases of the Gallbladder and Bile Ducts -- Section 3: Disorders of the Pancreas -- 370: Approach to the Patient with Pancreatic Disease -- 371: Acute and Chronic Pancreatitis -- Part 15: Immune-mediated, Inflammatory, and Rheumatologic Disorders -- Section 1: The Immune System in Health and Disease -- 372e: Introduction to the Immune System -- 373e: The Major Histocompatibility Complex -- 374: Primary Immune Deficiency Diseases -- 375e: Primary Immunodeficiencies Associated with (or Secondary to) Other Diseases -- Section 2: Disorders of Immune-Mediated Injury.

376: Allergies, Anaphylaxis, and Systemic Mastocytosis -- 377e: Autoimmunity and Autoimmune Diseases -- 378: Systemic Lupus Erythematosus -- 379: Antiphospholipid Syndrome -- 380: Rheumatoid Arthritis -- 381: Acute Rheumatic Fever -- 382: Systemic Sclerosis (Scleroderma) and Related Disorders -- 383: Sjögren's Syndrome -- 384: The Spondyloarthritides -- 385: The Vasculitis Syndromes -- 386e: Atlas of the Vasculitic Syndromes -- 387: Behçet’s Syndrome -- 388: Polymyositis, Dermatomyositis, and Inclusion Body Myositis -- 389: Relapsing Polychondritis -- 390: Sarcoidosis -- 391e: IgG4-Related Disease -- 392: Familial Mediterranean Fever and Other Hereditary Autoinflammatory Diseases -- Section 3: Disorders of the Joints and Adjacent Tissues -- 393: Approach to Articular and Musculoskeletal Disorders -- 394: Osteoarthritis -- 395: Gout and Other Crystal-Associated Arthropathies -- 396: Fibromyalgia -- 397: Arthritis Associated with Systemic Disease, and Other Arthritides -- 398: Periarticular Disorders of the Extremities -- Part 16: Endocrinology and Metabolism -- Section 1: Endocrinology -- 399: Approach to the Patient with Endocrine Disorders -- 400e: Mechanisms of Hormone Action -- 401e: Anterior Pituitary: Physiology of Pituitary Hormones -- 402: Hypopituitarism -- 403: Anterior Pituitary Tumor Syndromes -- 404: Disorders of the Neurohypophysis -- 405: Disorders of the Thyroid Gland -- 406: Disorders of the Adrenal Cortex -- 407: Pheochromocytoma -- 408: Multiple Endocrine Neoplasia -- 409: Autoimmune Polyendocrine Syndromes -- Section 2: Reproductive Endocrinology -- 410: Disorders of Sex Development -- 411: Disorders of the Testes and Male Reproductive System -- 412: Disorders of the Female Reproductive System -- 413: Menopause and Postmenopausal Hormone Therapy -- 414: Infertility and Contraception -- Section 3: Obesity, Diabetes Mellitus, and Metabolic Syndrome -- 415e: Biology of Obesity -- 416: Evaluation and Management of Obesity -- 417: Diabetes Mellitus: Diagnosis, Classification, and Pathophysiology -- 418: Diabetes Mellitus: Management and Therapies -- 419: Diabetes Mellitus: Complications -- 420: Hypoglycemia -- 421: Disorders of Lipoprotein Metabolism -- 422: The Metabolic Syndrome -- Section 4: Disorders of Bone and Mineral Metabolism -- 423: Bone and Mineral Metabolism in Health and Disease -- 424: Disorders of the Parathyroid Gland and Calcium Homeostasis -- 425: Osteoporosis -- 426e: Paget’s Disease and Other Dysplasias of Bone -- Section 5: Disorders of Intermediary Metabolism -- 427: Heritable Disorders of Connective Tissue -- 428: Hemochromatosis -- 429: Wilson’s Disease -- 430: The Porphyrias -- 431e: Disorders of Purine and Pyrimidine Metabolism -- 432e: Lysosomal Storage Diseases -- 433e: Glycogen Storage Diseases and Other Inherited Disorders of Carbohydrate Metabolism -- 434e: Inherited Disorders of Amino Acid Metabolism in Adults -- 435e: Inherited Defects of Membrane Transport -- 436e: Atlas of Clinical Manifestations of Metabolic Diseases -- Part 17: Neurologic Disorders -- Section 1: Diagnosis of Neurologic Disorders -- 437: Approach to the Patient with Neurologic Disease -- 438e: The Neurologic Screening Exam -- 439e: Video Atlas of the Detailed Neurologic Examination -- 440e: Neuroimaging in Neurologic Disorders -- 441e: Atlas of Neuroimaging -- 442e: Electrodiagnostic Studies of Nervous System Disorders: EEG, Evoked Potentials, and EMG.

443e: Technique of Lumbar Puncture -- 444e: Biology of Neurologic Diseases -- Section 2: Diseases of the Central Nervous System -- 445: Seizures and Epilepsy -- 446: Cerebrovascular Diseases -- 447: Migraine and Other Primary Headache Disorders -- 448: Alzheimer’s Disease and Other Dementias -- 449: Parkinson’s Disease and Other Movement Disorders -- 450: Ataxic Disorders -- 451e: Classification of the Spinocerebellar Ataxias -- 452: Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases -- 453e: Prion Diseases -- 454: Disorders of the Autonomic Nervous System -- 455: Trigeminal Neuralgia, Bell’s Palsy, and Other Cranial Nerve Disorders -- 456: Diseases of the Spinal Cord -- 457e: Concussion and Other Traumatic Brain Injuries -- 458: Multiple Sclerosis and Other Demyelinating Diseases -- Section 3: Nerve and Muscle Disorders -- 459: Peripheral Neuropathy -- 460: Guillain-Barré Syndrome and Other Immune-Mediated Neuropathies -- 461: Myasthenia Gravis and Other Diseases of the Neuromuscular Junction -- 462e: Muscular Dystrophies and Other Muscle Diseases -- 463e: Special Issues in Inpatient Neurologic Consultation -- Section 4: Chronic Fatigue Syndrome -- 464e: Chronic Fatigue Syndrome -- Section 5: Psychiatric and Addiction Disorders -- 465e: Biology of Psychiatric Disorders -- 466: Mental Disorders -- 467: Alcohol and Alcoholism -- 468e: Opioid-Related Disorders -- 469e: Cocaine and Other Commonly Abused Drugs -- 470: Nicotine Addiction -- 471e: Neuropsychiatric Illnesses in War Veterans -- Part 18: Poisoning, Drug Overdose, and Envenomation -- 472e: Heavy Metal Poisoning -- 473e: Poisoning and Drug Overdose -- 474: Disorders Caused by Venomous Snakebites and Marine Animal Exposures -- 475: Ectoparasite Infestations and Arthropod Injuries -- Part 19: Disorders Associated with Environmental Exposures -- 476e: Altitude Illness -- 477e: Hyperbaric and Diving Medicine -- 478e: Hypothermia and Frostbite -- 479e: Heat-Related Illnesses -- 480e: The Clinical Laboratory in Modern Health Care -- APPENDIX: Laboratory Values of Clinical Importance -- Part 20: Clinical Procedures Tutorials -- Brigham and Women's Hospital Series -- 481e: Clinical Procedure Tutorial: Central Venous Catheter Placement -- 482e: Clinical Procedure Tutorial: Thoracentesis -- 483e: Clinical Procedure Tutorial: Abdominal Paracentesis -- 484e: Clinical Procedure Tutorial: Endotracheal Intubation -- Mount Sinai School of Medicine Series -- Credit: Mount Sinai School of Medicine Series: Medical Editors: Sean Sadikot and Jeremy Matloff -- 485e: Clinical Procedures Tutorial: Percutaneous Arterial Blood Gas Sampling -- 486e: Clinical Procedures Tutorial: Lumbar Puncture -- 487e: Clinical Procedures Tutorial: Phlebotomy -- 488e: Clinical Procedures Tutorial: Insertion of Female Urethral Catheter -- 489e: Clinical Procedures Tutorial: Insertion of Male Urethral Catheter -- 490e: Clinical Procedures Tutorial: Fine Needle Aspiration of Breast Cyst -- 491e: Clinical Procedures Tutorial: IV Insertion -- 492e: Clinical Procedures Tutorial: Fine Needle Aspiration of Thyroid Nodules -- 493e: Clinical Procedures Tutorial: Gynecologic Examination with Pap Smear -- 494e: Clinical Procedures Tutorial: Knee Arthrocentesis -- 495e: Clinical Procedures Tutorial: Pericardiocentesis -- 496e: Clinical Procedures Tutorial: Bone Marrow Biopsy -- 497e: Clinical Procedures Tutorial: Basic Suturing.

The landmark text that has defined internal medicine for generations of clinicians and students - completely updated with a more streamlined, functional presentation.

Also issued in online and PDF version.

Description based on cover image and table of contents, viewed on Oct. 24, 2016.